题 目：Proportional odds model with varying coefficients for censored data

报告人：Prof.Xingwei Tong

School of Mathematical Sciences, Beijing Normal University

时 间：2009年6月17日下昼2：00-3：00

地 点：伟易博新楼217室 

摘要：In this article, we consider a proportional odds model, which allows one to examine

the extent to which covariates interact nonlinearly with an exposure variable for analysis

of right-censored data.

A local maximum likelihood approach is presented to estimate nonlinear interactions

(the coefficient functions) and the baseline function. The proposed estimators are shown

to be consistent and asymptotically normal with the asymptotic variance estimated

consistently. %of the local likelihood estimator can be consistently estimated.

Also, we develop local profile likelihood ratio method to construct confidence region of

coefficient functions. Simulation studies are conducted to evaluate the performances of

the proposed estimators, and compare the normal approximation based confidence regions and

local profile likelihood ratio based confidence regions. The method is illustrated with

Stanford heart transplant data.